abstract：:We examined the prevalence of novel acronyms in the titles of anaesthetic and related studies and the response of anaesthetists to them. We separately analysed trainee-led research projects in the UK supported by the Research and Audit Federation of Trainees (RAFT), and a 10-year cohort of papers identified using the ...

journal_title：Anaesthesia

authors： Weale J,Soysa R,Yentis SM

更新日期：2018-12-01 00:00:00

abstract：:Despite numerous guidelines on the management of anaemia in surgical patients, there is no pragmatic guidance for the diagnosis and management of anaemia and iron deficiency in the postoperative period. A number of experienced researchers and clinicians took part in a two-day expert workshop and developed the followin...

journal_title：Anaesthesia

authors： Muñoz M,Acheson AG,Bisbe E,Butcher A,Gómez-Ramírez S,Khalafallah AA,Kehlet H,Kietaibl S,Liumbruno GM,Meybohm P,Rao Baikady R,Shander A,So-Osman C,Spahn DR,Klein AA

更新日期：2018-11-01 00:00:00

abstract：:Animal data have demonstrated increased block duration after local anaesthetic injections in diabetic rat models. Whether the same is true in humans is currently undefined. We, therefore, undertook this prospective cohort study to test the hypothesis that type-2 diabetic patients suffering from diabetic peripheral neu...

journal_title：Anaesthesia

authors： Baeriswyl M,Taffé P,Kirkham KR,Bathory I,Rancati V,Crevoisier X,Cherix S,Albrecht E

更新日期：2018-09-01 00:00:00

abstract：:Postoperative sore throat has a negative impact on patient satisfaction and recovery. Benzydamine hydrochloride is a non-steroidal anti-inflammatory drug available for topical use. We performed a systematic review and meta-analysis to assess the efficacy and safety of topical application of benzydamine to prevent post...

journal_title：Anaesthesia

authors： Kuriyama A,Aga M,Maeda H

更新日期：2018-07-01 00:00:00

abstract：:The optimum time interval for 10 ml boluses of bupivacaine 0.0625% + fentanyl 2 μg.ml-1 as part of a programmed intermittent epidural bolus regimen has been found to be 40 min. This regimen was shown to be effective without the use of supplementary patient-controlled epidural analgesia boluses in 90% of women during t...

journal_title：Anaesthesia

authors： Zakus P,Arzola C,Bittencourt R,Downey K,Ye XY,Carvalho JC

更新日期：2018-04-01 00:00:00

abstract：:Loop diuretics remain a fundamental pharmacological therapy to remove excess fluid and improve symptom control in acute decompensated heart failure. Several recent randomised controlled trials have examined the clinical benefit of continuous vs. bolus furosemide in acute decompensated heart failure, but have reported ...

journal_title：Anaesthesia

authors： Ng KT,Yap JLL

更新日期：2018-02-01 00:00:00

abstract：:Acute risk change has been described as the difference in calculated mortality risk between the pre-operative and postoperative periods of cardiac surgery. We aimed to assess whether this was associated with long-term survival after cardiac surgery. We retrospectively analysed 22,570 cardiac surgical patients, with mi...

journal_title：Anaesthesia

authors： Coulson TG,Bailey M,Reid CM,Tran L,Mullany DV,Smith JA,Pilcher D

更新日期：2017-12-01 00:00:00

abstract：:Difficulty in tracheal intubation in paediatric intensive care patients is associated with increased morbidity and mortality. Delays to intubation and interruption to oxygenation and ventilation are poorly tolerated. We developed a safe and atraumatic tracheal intubation technique. A floppy-tipped guidewire and airway...

journal_title：Anaesthesia

authors： Cross D,Nyman A,James P,Durward A

更新日期：2017-11-01 00:00:00

abstract：:Capnography (ETCO2 ) is routinely used as a non-invasive estimate of arterial carbon dioxide (PaCO2 ) levels in order to modify ventilatory settings, whereby it is assumed that there is a positive gap between PaCO2 and ETCO2 of approximately 0.5 kPa. However, negative values (ETCO2 > PaCO2 ) can be observed. We retros...

journal_title：Anaesthesia

authors： Onodi C,Bühler PK,Thomas J,Schmitz A,Weiss M

更新日期：2017-11-01 00:00:00

abstract：:Some short procedures require deep neuromuscular blockade, which needs to be reversed at the end of the procedure. Forty-four patients undergoing elective laryngeal micro-surgery were randomly allocated into two groups: rocuronium 0.45 mg.kg-1 with neostigmine (50 μg.kg-1 with glycopyrrolate 10 μg.kg-1 ) reversal (mod...

journal_title：Anaesthesia

authors： Choi ES,Oh AY,Koo BW,Hwang JW,Han JW,Seo KS,Ahn SH,Jeong WJ

更新日期：2017-10-01 00:00:00

abstract：:The organisational state of inpatient pain management in UK hospitals is difficult to determine. We sent an electronic questionnaire to 209 acute pain service leads throughout the UK. Questions were about staffing and service provision. We received 141 responses (67%); 47% of all UK hospitals. Each service was respons...

journal_title：Anaesthesia

authors： Rockett M,Vanstone R,Chand J,Waeland D

更新日期：2017-10-01 00:00:00

abstract：:This prospective, observational study explored the need for pain-related unscheduled contact with healthcare services after outpatient surgery. We hypothesised that 10% of outpatients would have pain-related unscheduled contact with healthcare services, and that the incidence would differ depending on the type of surg...

journal_title：Anaesthesia

authors： Brix LD,Bjørnholdt KT,Thillemann TM,Nikolajsen L

更新日期：2017-07-01 00:00:00

abstract：:We tested whether prophylactic droperidol and ondansetron, in combination with a moderate dose of dexamethasone, were equally effective in reducing nausea and vomiting after tonsillectomy in children and that both were superior to saline with dexamethasone. We randomly allocated 300 children to intravenous saline, dro...

journal_title：Anaesthesia

authors： Flubacher P,Fournier N,Cherpillod J,Waridel F,Nydegger M,Albrecht E

更新日期：2017-07-01 00:00:00

abstract：:Pressure waveform analysis provides a reliable confirmatory adjunct to the loss-of-resistance technique to identify the epidural space during thoracic epidural anaesthesia, but its role remains controversial in lumbar epidural analgesia during labour. We performed an observational study in 100 labouring women of the s...

journal_title：Anaesthesia

authors： Al-Aamri I,Derzi SH,Moore A,Elgueta MF,Moustafa M,Schricker T,Tran DQ

更新日期：2017-07-01 00:00:00

abstract：:Forty anaesthetists calculated maximum permissible doses of eight local anaesthetic formulations for simulated patients three times with three methods: an electronic calculator; nomogram; and pen and paper. Correct dose calculations with the nomogram (85/120) were more frequent than with the calculator (71/120) or pen...

journal_title：Anaesthesia

authors： Walker JD,Williams N,Williams DJ

更新日期：2017-06-01 00:00:00

abstract：:Post-spinal hypotension remains a common and clinically-important problem during caesarean section, and accurate pre-operative prediction of this complication might enhance clinical management. We conducted a prospective, single-centre, observational study of heart rate variability in 102 patients undergoing elective ...

journal_title：Anaesthesia

authors： Bishop DG,Cairns C,Grobbelaar M,Rodseth RN

更新日期：2017-05-01 00:00:00

abstract：:We undertook an audit in a rural Ugandan hospital that describes the epidemiology and mortality of 5147 patients admitted to the intensive care unit. The most frequent admission diagnoses were postoperative state (including following trauma) (2014/5147; 39.1%), medical conditions (709; 13.8%) and traumatic brain injur...

journal_title：Anaesthesia

authors： Dünser MW,Towey RM,Amito J,Mer M

更新日期：2017-02-01 00:00:00

abstract：:A predicted difficult airway is sometimes considered a contra-indication to rapid sequence induction of general anaesthesia, even in an urgent case such as a category-1 caesarean section for fetal distress. However, formally assessing the risk is difficult because of the rarity and urgency of such cases. We have used ...

journal_title：Anaesthesia

authors： Krom AJ,Cohen Y,Miller JP,Ezri T,Halpern SH,Ginosar Y

更新日期：2017-02-01 00:00:00

abstract：:The aim of this study was to develop an audit tool to identify prospectively all peri-operative adverse events during airway management in a cost-effective and reproducible way. All patients at VU University Medical Center who required general anaesthesia for elective and emergency surgical procedures were included du...

journal_title：Anaesthesia

authors： Huitink JM,Lie PP,Heideman I,Jansma EP,Greif R,van Schagen N,Schauer A

更新日期：2017-01-01 00:00:00

abstract：:Here, we describe proof of concept of a novel method for delivering volatile anaesthetics, where the liquid anaesthetic (sevoflurane or isoflurane) is formulated into an emulsion that is contained in a compact, lightweight device through which carrier gas flows. Release of anaesthetic is achieved by stirring of the fo...

journal_title：Anaesthesia

authors： Paul A,Clark JN,Salama IE,Jenkins BJ,Goodwin N,Wilkes AR,Mahoney PF,Hall JE

更新日期：2017-01-01 00:00:00

abstract：:Unrecognised postoperative residual neuromuscular block remains a frequent occurrence in recovery rooms. Evidence indicates that current practice continues to perpetuate the status quo, in which 10-40% of patients experience postoperative residual weakness. A departure from the current practice requires small efforts ...

journal_title：Anaesthesia

authors： Naguib M,Brull SJ,Johnson KB

更新日期：2017-01-01 00:00:00

abstract：:Atrial fibrillation is the most frequent arrhythmia after thoracic surgery and is associated with increased hospital costs, morbidity and mortality. In this study, we aimed to identify potentially modifiable risk factors for postoperative atrial fibrillation following lung resection surgery and to suggest possible mea...

journal_title：Anaesthesia

authors： Lee SH,Ahn HJ,Yeon SM,Yang M,Kim JA,Jung DM,Park JH

更新日期：2016-12-01 00:00:00

abstract：:Implementation of a quality improvement bundle for peri-operative management of emergency laparotomy (ELPQuIC) improved mortality in a previous study. We used data from one site that participated in that study to examine whether it was associated with the cost of care. We collected data from 396 patients: 144 before, ...

journal_title：Anaesthesia

authors： Eveleigh MO,Howes TE,Peden CJ,Cook TM

更新日期：2016-11-01 00:00:00

abstract：:The unique pharmacology of remifentanil makes it a popular intra-operative analgesic. Short-acting opioids like remifentanil have been associated with acute opioid tolerance and/or opioid-induced hyperalgesia, two phenomena which have different mechanisms and are pharmacologically distinct. Clinical studies show heter...

journal_title：Anaesthesia

authors： Yu EH,Tran DH,Lam SW,Irwin MG

更新日期：2016-11-01 00:00:00

abstract：:Compared with a lightwand which is used blind, Optiscope™ , a rigid video-stylet, can provide direct imaging of airway structures, potentially offering improved conditions in cervical spine-immobilised patients. We randomly assigned 168 patients who required cervical immobilisation during tracheal intubation to use of...

journal_title：Anaesthesia

authors： Seo H,Kim E,Son JD,Ji S,Min SW,Park HP

更新日期：2016-11-01 00:00:00

abstract：:Point-of-care coagulation monitoring can be used for the guidance of haemostasis management. However, the influence of time on point-of-care prothrombin time testing following protamine administration after cardiopulmonary bypass has not been investigated. Bland-Altman and error grid analysis were used to analyse the ...

journal_title：Anaesthesia

authors： Meesters MI,Kuiper G,Vonk AB,Loer SA,Boer C

更新日期：2016-10-01 00:00:00

abstract：:To assess the degree to which cricoid pressure (Sellick manoeuvre) actually compresses the oesophagus, we measured the effect of cricoid pressure and paralaryngeal pressure on the outer anteroposterior diameter of the upper oesophagus with ultrasound in 39 healthy volunteers. The mean (SD) outer anteroposterior oesoph...

journal_title：Anaesthesia

authors： Andruszkiewicz P,Wojtczak J,Wroblewski L,Kaczor M,Sobczyk D,Kowalik I

更新日期：2016-09-01 00:00:00

abstract：:We thought that delirium might be less frequent after transcatheter aortic valve implantation via the femoral artery compared with via the cardiac apex. We reviewed 210 patients who underwent transcatheter aortic valve implantation between January 2009 and October 2014. The proportion (95% CI) of patients who suffered...

journal_title：Anaesthesia

authors： Sharma V,Katznelson R,Horlick E,Osten M,Styra R,Cusimano RJ,Carroll J,Djaiani G

更新日期：2016-08-01 00:00:00

abstract：:Excessive neck flexion and rotation in certain surgical positions may cause kinking of the internal jugular vein that obstructs cerebral venous blood flow and results in elevated intracranial pressure. The objective of this study was to measure internal jugular vein flow and identify potential impediments to venous fl...

journal_title：Anaesthesia

authors： Yeoh TY,Tan A,Manninen P,Chan VW,Venkatraghavan L

更新日期：2016-07-01 00:00:00

abstract：:This study aimed to assess the association between caudal block and postoperative complications after tubularised incised plate urethroplasty. The medical records of 388 paediatric patients who underwent urethroplasty at a tertiary medical centre were analysed retrospectively. Among the 342 patients included, 216 pati...

journal_title：Anaesthesia

authors： Kim MH,Im YJ,Kil HK,Han SW,Joe YE,Lee JH

更新日期：2016-07-01 00:00:00

abstract：:We assessed the effectiveness of early patient-controlled oral analgesia compared with parenteral analgesia in a randomised controlled non-inferiority trial of women undergoing elective caesarean section under regional anaesthesia. Seventy-seven women received multimodal paracetamol, ketoprofen and morphine analgesia....

journal_title：Anaesthesia

authors： Bonnal A,Dehon A,Nagot N,Macioce V,Nogue E,Morau E

更新日期：2016-05-01 00:00:00

abstract：:We conducted this study to determine if placement of infraclavicular catheters guided by ultrasound is quicker than placement guided by nerve stimulation. Infraclavicular brachial plexus catheters were inserted in 210 randomly allocated patients who were scheduled for elective hand or elbow surgery. Needle and cathete...

journal_title：Anaesthesia

authors： Dhir S,Armstrong K,Armstrong P,Bouzari A,Mall J,Yu J,Ganapathy S,King G

更新日期：2016-02-01 00:00:00

abstract：:Isotonic saline is a widely-used infusion fluid, although the associated chloride load may cause metabolic acidosis and impair kidney function in young, healthy volunteers. We wished to examine whether these effects also occurred in the elderly, and conducted a crossover study in 13 men with a mean age of 73 years (ra...

journal_title：Anaesthesia

authors： Hahn RG,Isacson MN,Fagerström T,Rosvall J,Nyman CR

更新日期：2016-02-01 00:00:00

abstract：:A can't intubate, can't ventilate scenario can result in morbidity and death. Although a rare occurrence (1:50 000 general anaesthetics), it is crucial that anaesthetists maintain the skills necessary to perform cricothyroidotomy, and are well-equipped with appropriate tools. We undertook a bench study comparing a new...

journal_title：Anaesthesia

authors： King W,Teare J,Vandrevala T,Cartwright S,Mohammed KB,Patel B

更新日期：2016-02-01 00:00:00

abstract：:Recovery is an abstract quantity the definition of which varies according to the pre-dilection of individual institutions, clinicians or patients. While traditionally focused on immediate postoperative restitution of function and readiness for discharge, recovery assessment has progressively expanded its focus to incl...

journal_title：Anaesthesia

authors： Bowyer AJ,Royse CF

更新日期：2016-01-01 00:00:00

abstract：:We report 13 cases of presumed rocuronium-induced anaphylaxis in which sugammadex was administered with the intention of reversing the immunological reaction. Of these 13 cases, eight (62%) were later confirmed to be type-1 hypersensitivity reactions to rocuronium, three (23%) were triggered by an antibiotic and two (...

journal_title：Anaesthesia

authors： Platt PR,Clarke RC,Johnson GH,Sadleir PH

更新日期：2015-11-01 00:00:00

abstract：:We undertook the first clinical evaluation of a novel, non-invasive device for the continuous measurement of plasma haemoglobin concentration in 25 patients undergoing elective cardiac surgery. At four pre-determined intervals, samples of blood were taken for plasma haemoglobin estimation on a blood gas analyser and a...

journal_title：Anaesthesia

authors： Broderick AJ,Desmond F,Leen G,Shorten G

更新日期：2015-10-01 00:00:00

abstract：:We hypothesised that the genetic effect of single nucleotide polymorphisms in the TACR1 gene, which encodes NK1 receptors, could influence the sex difference in postoperative nausea and vomiting. Thirty-two selected single nucleotide polymorphisms were genotyped by the Sanger sequencing method in 200 patients who unde...

journal_title：Anaesthesia

authors： Hayase T,Sugino S,Moriya H,Yamakage M

更新日期：2015-10-01 00:00:00

abstract：:Difficult airway practice guidelines include the use of a supraglottic airway device as part of the armamentarium to provide and maintain ventilation and oxygenation. We retrospectively reviewed 14 480 patients aged ≥ 18 years who underwent general anaesthesia. We identified 74 (0.5%) patients whose lungs were identif...

journal_title：Anaesthesia

authors： Saito T,Liu W,Chew ST,Ti LK

更新日期：2015-09-01 00:00:00

abstract：:In a previous paper, one of the authors (JBC) used a chi-squared method to analyse the means (SD) of baseline variables, such as height or weight, from randomised controlled trials by Fujii et al., concluding that the probabilities that the reported distributions arose by chance were infinitesimally small. Subsequent ...

journal_title：Anaesthesia

authors： Carlisle JB,Dexter F,Pandit JJ,Shafer SL,Yentis SM

更新日期：2015-07-01 00:00:00